Hawthorn defender Jarman Impey is all set to take his place in the side that will take on St Kilda at the MCG on Sunday.
Having made a promising return through the VFL last week, the 26-year-old will play his first senior game since Round 14 last year.
Daniel Howe has also been named in the 22 after being the medical substitute against Carlton in Round 3.
Howe was activated at quarter time last week following concerns of a scapula injury to teammate Jack Scrimshaw.
Scans have since cleared Scrimshaw of injury though and the 23-year-old will remain in the starting line-up for the Hawks.
Chad Wingard (calf) and Finn Maginness (omitted) are the pair that will make way for the incoming duo.
This week's match-up with the Saints will mark the first meeting at the MCG between the two clubs since 2014.
ROUND 4 TEAM
Hawthorn v St Kilda
Sunday April 10, 3.20pm AEST
B: Blake Hardwick, Sam Frost, Denver Grainger-Barras
HB: Changkuoth Jiath, James Sicily, Will Day
C: Harry Morrison, Jaeger O'Meara, Daniel Howe
HF: Connor Macdonald, Jai Newcombe, Dylan Moore
F: Luke Breust, Mitch Lewis, Jack Gunston
R: Ned Reeves, Tom Mitchell, Josh Ward
INT: Conor Nash, Jack Scrimshaw, James Worpel, Jarman Impey
Emer: Emerson Jeka, Tom Phillips, Finn Maginness, Jacob Koschitzke
In: Impey, Howe
Out: Wingard (calf), Maginness