Along with Hodge fellow 2013 premiership players Josh Gibson and Brad Sewell will also play their first matches for the year.
The only changes from last week's squad are the omissions of Paul Puopolo, Taylor Duryea and Billy Hartung.
Hawthorn v North Melbourne
NAB Challenge Round 2
Friday 21 February
7.10pm, Aurora Stadium
Hawthorn Squad:
2. Roughead
3. Lewis
4. Suckling
5. Mitchell
6. Gibson
7. McEvoy
9. Burgoyne
10. Hill
12. Sewell
13. Cheney
15. Hodge
16. Smith
18. Ceglar
19. Gunston
20. Hale
21. Ross
22. Breust
23. O’Brien
26. Shiels
29. Langford
30. Lowden
31. Litherland
32. Simpkin
33. Rioli
35. Grimley
36. Wanganeen
38. Hallahan
39. Woodward
46. Heatherley
North Melbourne Squad:
1. Daniel Currie
2. Brad McKenzie
3. Ryan Bastinac
5. Ben Jacobs
6. Lachlan Hansen
7. Jack Ziebell
8. Daniel Wells
10.Ben Cunnington
12. Lindsay Thomas
14. Trent Dumont
15. Nick Dal Santo
16. Scott Thompson
18. Shaun Atley
19. Sam Wright
20. Drew Petrie
21. Luke McDonald
22. Todd Goldstein
27. Taylor Garner
28. Robin Nahas
29. Brent Harvey
31. Cam Delaney
34. Jamie MacMillan
35. Aaron Black
36, Joel Tippett
38. Majak Daw
41. Aaron Mullett
42. Scott McMahon
43. Sam Gibson
44. Max Warren